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Andy Highton awarded Kia Niwha Leader Fellowship

Congratulations to Gut Health Network member, Andy Highton, who was awarded a Kia Niwha Leader Fellowship

https://www.teniwha.com/news/kia-niwha-leader-fellowships-announced

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Vedolizumab supports intestinal stem cell recovery.

A recent study from the University of California, San Francisco showed that Vedolizumab (VDZ), an anti-integrin antibody, effective in the treatment for Colitis, plays an important role in limiting specific inflammatory immune, fibroblasts and endothelial cells to facilitate intestinal epithelial stem cell recovery. By using a combination of latest sequencing technologies, they provide a tool for comprehensive analysis of the inter cellular networks of the colon in health, disease, and during treatment. Implementing these new single-cell and spatial technologies simultaneously in individual patients will lead to more precise treatment algorithms, and therefore a way for precision medicine.

Click on the link below to see the study

https://www.nature.com/articles/s41467-024-45665-6?fromPaywallRec=false#Sec2

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Gut bacteria break down cholesterol

In a new study, researchers found that gut bacteria can break down cholesterol. They identified  bacteria in the human gut that have an enzyme that can convert cholesterol into a form that isn't absorbed by the body. The study supports previous work indicating a link between bacterial enzymes that can modify cholesterol. This research could potentially be used to develop probiotic-type treatments to replace or support traditional treatments for managing cholesterol, like statins.

For a summary of the research, click here

For the whole research paper, click here

Blog image credit:  Susanna Hamilton, Broad Communications

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IBDSmart app update

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We are back!

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The Gut-Brain Axis

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